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Article

Recurrent genetic defects in classical Hodgkin lymphoma cell lines.

Leukemia & lymphoma - 1 Dec 2016

Hudnall S David, Meng Hailong, Lozovatsky Larissa, Li Peining, Strout Matthew, Kleinstein Steven H

Abstract excerpt

Genetic analysis of classical Hodgkin lymphoma (cHL) has been hampered by the paucity of Hodgkin cells in biopsies and their poor growth in vitro. However, a wealth of information has been obtained from cHL cell lines. Here we report results of whole-exome sequencing and karyotypic analysis of five cHL cell lines. Four genes with potentially pathogenic single nucleotide variants (SNV) were detected in three cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27121023
DOI: 10.1080/10428194.2016.1177179

Genes

NCAPD2
PLK4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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