Article
The evolutionary puzzle of Escherichia coli ST131.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2020
Pitout Johann D D, Finn Thomas J
Abstract excerpt
The abrupt expansion of Escherichia coli sequence type (ST) 131 is unmatched among Gram negative bacteria. In many ways, ST131 can be considered a real-world model for the complexities involved in the evolution of a multidrug resistant pathogen. While much progress has been made on our insights into the organism's population structure, pathogenicity and drug resistance profile, significant gaps in our knowledge...
Topics
- Animals
- Drug Resistance, Multiple, Bacterial
- Escherichia coli
- Escherichia coli Infections
- Genome, Bacterial
- Humans
- Mutation
- Plasmids