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Article

Correlation of Aqueous Humor Lysyl Oxidase Activity with TGF-ß Levels and LOXL1 Genotype in Pseudoexfoliation.

Current eye research - 1 Oct 2016

Gayathri Ramakrishnan, Coral Karunakaran, Sharmila Ferdinamarie, Sripriya Sarangapani, Sripriya Krishnamoorthy, Manish Panday, Shantha B, Ronnie George, Vijaya Lingam, Narayanasamy Angayarkanni

Abstract excerpt

PURPOSE: Pseudoexfoliation (PXF) is a microfibrillopathy involving disordered elastogenesis. Abnormal extracellular matrix (ECM) production underlies the pathophysiology of PXF. The enzyme Lysyl oxidase (LOX) and its isoforms are known to cross-link the elastin and collagen. Though the etiopathogensis of PXF is not well understood, studies report on the genetic risk involving LOXL1 gene. This study aims to screen...

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Source

Identifiers

PMID: 27116380
DOI: 10.3109/02713683.2015.1125505

Genes

LOX
LOXL1
LOXL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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