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Article

Genotype-correlated expression of lysyl oxidase-like 1 in ocular tissues of patients with pseudoexfoliation syndrome/glaucoma and normal patients.

The American journal of pathology - 1 Dec 2008

Schlötzer-Schrehardt Ursula, Pasutto Francesca, Sommer Pascal, Hornstra Ian, Kruse Friedrich E, Naumann Gottfried O H, Reis André, Zenkel Matthias

Abstract excerpt

Pseudoexfoliation (PEX) syndrome is a generalized disease of the extracellular matrix and the most common identifiable cause of open-angle glaucoma. Two single nucleotide polymorphisms in the lysyl oxidase-like 1 (LOXL1) gene (rs1048661 and rs3825942) have been recently identified as strong genetic risk factors for both PEX syndrome and PEX glaucoma. Here we investigated the expression and localization of LOXL1,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Amino Acid Oxidoreductases
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Source

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Identifiers

PMID: 18974306
DOI: 10.2353/ajpath.2008.080535
PMCID: PMC2626384

Genes

LOXL1
LOX
LOXL2

Provenance

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Genotype-correlated expression of lysyl oxidase-like 1 in ocular tissues of patients with pseudoexfoliation syndrome/glaucoma and normal patients.PMID 18974306Read ↗

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