Article
Mucus Hyperconcentration as a Unifying Aspect of the Chronic Bronchitic Phenotype.
Annals of the American Thoracic Society - 1 Apr 2016
Button Brian, Anderson Wayne H, Boucher Richard C
Abstract excerpt
Abnormalities in mucus production and qualitative properties such as mucus hydration are central to the pathophysiology of airway disease including cystic fibrosis, asthma, and chronic bronchitis. In vitro air-liquid interface epithelial cell cultures demonstrate direct relationships between mucociliary transport, periciliary liquid (PCL) height, and mucus concentration (expressed as percent solids or partial...
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