Article
Cystic fibrosis: a disease of vulnerability to airway surface dehydration.
Trends in molecular medicine - 1 Jun 2007
Boucher Richard C
Abstract excerpt
Cystic fibrosis (CF) lung disease involves chronic bacterial infection of retained airway secretions (mucus). Recent data suggest that CF lung disease pathogenesis reflects the vulnerability of airway surfaces to dehydration and collapse of mucus clearance. This predisposition is caused by mutati...
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