Article
Molecular response and association analysis of Megalobrama amblycephala fih-1 with hypoxia.
Molecular genetics and genomics : MGG - 1 Aug 2016
Zhang Bao, Chen Nan, Huang Cuihong, Huang Chunxiao, Chen Boxiang, Liu Hong, Wang Weimin, Gul Yasmeen, Wang Huanling
Abstract excerpt
Hypoxia is one of the most important environmental factors which affect fish growth, development and survival, but regulation mechanisms of hypoxia in fish remain unclear. Therefore, to further understand molecular functions of factor inhibiting HIF-1 (Fih-1), an essential hypoxia sensor, the full-length cDNA of fih-1 was cloned from Megalobrama amblycephala, a hypoxia-sensitive cyprinid fish. The deduced amino...
Topics
- Animals
- Cloning, Molecular
- Cyprinidae
- Embryonic Development
- Gene Expression Regulation, Developmental
- Hypoxia
- Hypoxia-Inducible Factor 1
- Phylogeny
- Polymorphism, Single Nucleotide
- Promoter Regions, Genetic
- Sequence Analysis, DNA
- Sequence Analysis, Protein