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Article

Oxygen homeostasis

2 Nov 2009

Abstract excerpt

Abstract Metazoan life is dependent upon the utilization of O 2 for essential metabolic processes and oxygen homeostasis is an organizing principle for understanding metazoan evolution, ontology, physiology, and pathology. Hypoxia‐inducible factor 1 (HIF‐1) is a transcription factor that is expressed by all metazoan species and functions as a master regulator of oxygen homeostasis. Recent studies have elucidated...

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PMID: 20836033
DOI: 10.1002/wsbm.69

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