Article
Abnormal Osmotic Avoidance Behavior in C. elegans Is Associated with Increased Hypertonic Stress Resistance and Improved Proteostasis.
PloS one - 1 Jan 2016
Lee Elaine C, Kim Heejung, Ditano Jennifer, Manion Dacie, King Benjamin L, Strange Kevin
Abstract excerpt
Protein function is controlled by the cellular proteostasis network. Proteostasis is energetically costly and those costs must be balanced with the energy needs of other physiological functions. Hypertonic stress causes widespread protein damage in C. elegans. Suppression and management of protein damage is essential for optimal survival under hypertonic conditions. ASH chemosensory neurons allow C. elegans to...
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