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Article

[Activity of glial cells in the olfactory bulb of Niemann-Pick disease type C1 mice].

Sheng li xue bao : [Acta physiologica Sinica] - 25 Apr 2016

Yan Xin, Qiao Liang, Yang En-Hui, Lin Jun-Tang

Abstract excerpt

To study the pathological mechanisms of Niemann-Pick disease type C1, we observed the changes of activation of glial cells in the olfactory bulb of Npc1 mutant (Npc1(-/-)) mice. The genomic DNA was extracted from mouse tails for genotyping by PCR. Immunofluorescent histochemistry was performed to examine the activation of microglia and astrocytes in the olfactory bulb of Npc1(-/-) mice on postnatal day 30. NeuN,...

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Source

Identifiers

PMID: 27108900

Genes

CD68
DCX
GFAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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