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Article

Current knowledge of the multifunctional 17β-hydroxysteroid dehydrogenase type 1 (HSD17B1).

Gene - 15 Aug 2016

He Wanhong, Gauri Misra, Li Tang, Wang Ruixuan, Lin Sheng-Xiang

Abstract excerpt

At the late 1940s, 17β-HSD1 was discovered as the first member of the 17β-HSD family with its gene cloned. The three-dimensional structure of human 17β-HSD1 is the first example of any human steroid converting enzyme. The human enzyme's structure and biological function have thus been studied extensively in the last two decades. In humans, the enzyme is expressed in placenta, ovary, endometrium and breast. The...

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Identifiers

PMID: 27102893
DOI: 10.1016/j.gene.2016.04.031
PMCID: PMC6649686

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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