Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Friend or enemy? Review of 17β-HSD10 and its role in human health or disease.

Journal of neurochemistry - 1 Nov 2020

Vinklarova Lucie, Schmidt Monika, Benek Ondrej, Kuca Kamil, Gunn-Moore Frank, Musilek Kamil

Abstract excerpt

17β-hydroxysteroid dehydrogenase (17β-HSD10) is a multifunctional human enzyme with important roles both as a structural component and also as a catalyst of many metabolic pathways. This mitochondrial enzyme has important functions in the metabolism, development and aging of the neural system, where it is involved in the homeostasis of neurosteroids, especially in regard to estradiol, changes in which make it an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3-Hydroxyacyl CoA Dehydrogenases
Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Health Status

Share to Mitochondria

Share to Mutation

Share to Neoplasms

Share to Neurodegenerative Diseases

Share to Protein Structure, Secondary

Source

Identifiers

PMID: 32306391
DOI: 10.1111/jnc.15027

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Friend or enemy? Review of 17β-HSD10 and its role in human health or disease.PMID 32306391Read ↗

Perspectives in understanding the role of human 17beta-hydroxysteroid dehydrogenases in health and disease.Semantic proximity Read ↗

Current knowledge of the multifunctional 17β-hydroxysteroid dehydrogenase type 1 (HSD17B1).Semantic proximity Read ↗

17β-Hydroxysteroid Dehydrogenases: Physiological Roles in Health and DiseaseSemantic proximity Read ↗

HSD17B10: A gene involved in cognitive function through metabolism of isoleucine and neuroactive steroidsSemantic proximity Read ↗

HSD10 disease: clinical consequences of mutations in the HSD17B10 gene.Semantic proximity Read ↗

The diversity of sex steroid action: novel functions of hydroxysteroid (17β) dehydrogenases as revealed by genetically modified mouse models.Semantic proximity Read ↗

Design and validation of specific inhibitors of 17 -hydroxysteroid dehydrogenases for therapeutic application in breast and prostate cancer, and in endometriosisSemantic proximity Read ↗

11 beta-Hydroxysteroid dehydrogenase.Semantic proximity Read ↗

11β-Hydroxysteroid dehydrogenases and the brain: From zero to hero, a decade of progressSemantic proximity Read ↗

Abundant type 10 17β-hydroxysteroid dehydrogenase in the hippocampus of mouse Alzheimer’s disease modelSemantic proximity Read ↗

The first case in Asia of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (HSD10 disease) with atypical presentationSemantic proximity Read ↗

11β-Hydroxysteroid dehydrogenase 1: translational and therapeutic aspects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.