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Article

FRET reveals multiple interaction states between two component signalling system proteins of M. tuberculosis.

Biochimica et biophysica acta - 1 Jul 2016

Agrawal Ruchi, Kumar V Prem, Ramanan Harini, Saini Deepak Kumar

Abstract excerpt

BACKGROUND: Two component signalling involves interaction between sensor kinase (SK) and response regulator (RR) proteins which depends on their phosphorylation status. METHODS: In this study we report the development of an in vitro FRET assay for studying interaction between fluorescently tagged SK and RR proteins. RESULTS: Using TCS proteins of Mycobacterium tuberculosis, we demonstrate that phosphorylation...

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PMID: 27102281
DOI: 10.1016/j.bbagen.2016.04.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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