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Article

The sensor kinase MprB is required for Rhodococcus equi virulence.

Veterinary microbiology - 10 Jan 2011

MacArthur Iain, Parreira Valeria R, Lepp Dion, Mutharia Lucy M, Vazquez-Boland José A, Prescott John F

Abstract excerpt

Rhodococcus equi is a soil bacterium and, like Mycobacterium tuberculosis, a member of the mycolata. Through possession of a virulence plasmid, it has the ability to infect the alveolar macrophages of foals, resulting in pyogranulomatous bronchopneumonia. The virulence plasmid has an orphan two-component system (TCS) regulatory gene, orf8, mutation of which completely attenuates virulence. This study attempted to...

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Identifiers

PMID: 20637548
DOI: 10.1016/j.vetmic.2010.06.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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