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A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types

2016-11-07

Abstract excerpt

Semi-automated genome annotation methods such as Segway enable understanding of chromatin activity. Here we present chromatin state annotations of 164 human cell types using 1,615 genomics data sets. To produce these annotations, we developed a fully-automated annotation strategy in which we train separate unsupervised annotation models on each cell type and use a machine learning classifier to automate the state...

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Identifiers and source

Literature Corpus work
1e67f422-96c4-5967-8a26-7e937a2b1943
DOI
10.1101/086025
Open publication

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A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell typesDOI 10.1101/086025
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