Article
Integrating Genetic, Neuropsychological and Neuroimaging Data to Model Early-Onset Obsessive Compulsive Disorder Severity.
PloS one - 1 Jan 2016
Mas Sergi, Gassó Patricia, Morer Astrid, Calvo Anna, Bargalló Nuria, Lafuente Amalia, Lázaro Luisa
Abstract excerpt
We propose an integrative approach that combines structural magnetic resonance imaging data (MRI), diffusion tensor imaging data (DTI), neuropsychological data, and genetic data to predict early-onset obsessive compulsive disorder (OCD) severity. From a cohort of 87 patients, 56 with complete information were used in the present analysis. First, we performed a multivariate genetic association analysis of OCD...
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