Article
Quantifying dimensional severity of obsessive-compulsive disorder for neurobiological research.
Progress in neuro-psychopharmacology & biological psychiatry - 3 Oct 2017
Shavitt Roseli G, Requena Guaraci, Alonso Pino, Zai Gwyneth, Costa Daniel L C, de Bragança Pereira Carlos Alberto, do Rosário Maria Conceição, Morais Ivanil, Fontenelle Leonardo, Cappi Carolina, Kennedy James, Menchon Jose M, Miguel Euripedes, Richter Peggy M A
Abstract excerpt
Current research to explore genetic susceptibility factors in obsessive-compulsive disorder (OCD) has resulted in the tentative identification of a small number of genes. However, findings have not been readily replicated. It is now broadly accepted that a major limitation to this work is the heterogeneous nature of this disorder, and that an approach incorporating OCD symptom dimensions in a quantitative manner...
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