Article

Polygenic Risk Scores for Pediatric Obsessive-Compulsive Symptoms and their Mediating Effect in Clinically Diagnosed Samples of Obsessive-Compulsive Disorder, Attention-Deficit/Hyperactivity Disorder, Anxiety, Depression, Autism and Tourette syndrome

2025-08-06

Abstract excerpt

<title>Abstract</title> <p>Here, we present the first genome-wide association study of obsessive-compulsive symptoms in a sample of clinically diagnosed pediatric participants and healthy controls. Using a psychiatric questionnaire score as a quantitative trait we conducted a large-scale genetic analysis and ran multiple post-association analyses to investigate the mediating role of obsessive-compulsive symptoms...

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Literature Corpus work: 5136a10b-f4fc-51e5-9426-02ceecf824fa
DOI: 10.21203/rs.3.rs-7115885/v1

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