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Article

Dync1h1 Mutation Causes Proprioceptive Sensory Neuron Loss and Impaired Retrograde Axonal Transport of Dorsal Root Ganglion Neurons.

CNS neuroscience & therapeutics - 1 Jul 2016

Zhao Jing, Wang Yi, Xu Huan, Fu Yuan, Qian Ting, Bo Deng, Lu Yan-Xin, Xiong Yi, Wan Jun, Zhang Xiang, Dong Qiang, Chen Xiang-Jun

Abstract excerpt

BACKGROUND AND PURPOSE: Sprawling (Swl) is a radiation-induced mutation which has been identified to have a nine base pair deletion in dynein heavy chain 1 (DYNC1H1: encoded by a single gene Dync1h1). This study is to investigate the phenotype and the underlying mechanism of the Dync1h1 mutant. METHODS AND RESULTS: To display the phenotype of Swl mutant mice, we examined the embryos of homozygous (Swl/Swl) and...

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Identifiers

PMID: 27080913
DOI: 10.1111/cns.12552
PMCID: PMC6492895

Genes

NGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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