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Article

A large family of Dscam genes with tandemly arrayed 5' cassettes in Chelicerata.

Nature communications - 15 Apr 2016

Yue Yuan, Meng Yijun, Ma Hongru, Hou Shouqing, Cao Guozheng, Hong Weiling, Shi Yang, Guo Pengjuan, Liu Baoping, Shi Feng, Yang Yun, Jin Yongfeng

Abstract excerpt

Drosophila Dscam1 (Down Syndrome Cell Adhesion Molecules) and vertebrate clustered protocadherins (Pcdhs) are two classic examples of the extraordinary isoform diversity from a single genomic locus. Dscam1 encodes 38,016 distinct isoforms via mutually exclusive splicing in D. melanogaster, while the vertebrate clustered Pcdhs utilize alternative promoters to generate isoform diversity. Here we reveal a shortened...

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Identifiers

PMID: 27080167
DOI: 10.1038/ncomms11252
PMCID: PMC4835542

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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