Article
Multi-locus genetic risk score predicts risk for Crohn's disease in Slovenian population.
World journal of gastroenterology - 14 Apr 2016
Zupančič Katarina, Skok Kristijan, Repnik Katja, Weersma Rinse K, Potočnik Uroš, Skok Pavel
Abstract excerpt
AIM: To develop a risk model for Crohn's disease (CD) based on homogeneous population. METHODS: In our study were included 160 CD patients and 209 healthy individuals from Slovenia. The association study was performed for 112 single nucleotide polymorphisms (SNPs). We generated genetic risk scores (GRS) based on the number of risk alleles using weighted additive model. Discriminatory accuracy was measured by area...
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