Enterovirus D68 capsid formation and stability requires acidic compartments

Abstract excerpt

Enterovirus D68 (EV-D68), a picornavirus traditionally associated with respiratory infections, has recently been linked to a polio-like paralytic condition known as acute flaccid myelitis (AFM). EV-D68 is understudied, and much of the field’s understanding of this virus is based on studies of poliovirus. For poliovirus, we previously showed that low pH promotes virus capsid maturation, but here we show that, for E...

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• Autophagy in Disease and Therapy
• CRISPR and Genetic Engineering
• Cytomegalovirus and herpesvirus research
• HIV Research and Treatment
• Mosquito-borne diseases and control
• RNA regulation and disease
• Viral gastroenteritis research and epidemiology
• Viral Infections and Immunology Research

Identifiers and source

Literature Corpus work

c246318a-9230-5b97-966b-230b9d164295

DOI

10.1101/2023.06.12.544695