Article
Serotype-Specific Regulation of Dengue Virus NS5 Protein Subcellular Localization
29 May 2024
Abstract excerpt
High Resolution Image Download MS PowerPoint Slide Dengue virus (DENV) nonstructural protein 5 (NS5), consisting of methyltransferase and RNA-dependent RNA polymerase (RdRp) domains, is critical for viral RNA synthesis within endoplasmic reticulum-derived replication complexes in the cytoplasm. However, a significant proportion of NS5 is localized to the nucleus of infected cells for DENV2, 3, and 4, whereas...
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