Article
Development of a highly metastatic model that reveals a crucial role of fibronectin in lung cancer cell migration and invasion.
BMC cancer - 9 Jul 2010
Jia Deshui, Yan Mingxia, Wang Xiaomin, Hao Xiangfang, Liang Linhui, Liu Lei, Kong Hanwei, He Xianghuo, Li Jinjun, Yao Ming
Abstract excerpt
BACKGROUND: The formation of metastasis is the most common cause of death in patients with lung cancer. A major implement to understand the molecular mechanisms involved in lung cancer metastasis has been the lack of suitable models to address it. In this study, we aimed at establishing a highly metastatic model of human lung cancer and characterizing its metastatic properties and underlying mechanisms. METHODS:...
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