Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrative analysis of two cell lines derived from a non-small-lung cancer patient--a panomics approach.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2014

Mayba Oleg, Gnad Florian, Peyton Michael, Zhang Fan, Walter Kimberly, Du Pan, Huntley Melanie A, Jiang Zhaoshi, Liu Jinfeng, Haverty Peter M, Gentleman Robert C, Li Ruiqiang, Minna John D, Li Yingrui, Shames David S, Zhang Zemin

Abstract excerpt

Cancer cells derived from different stages of tumor progression may exhibit distinct biological properties, as exemplified by the paired lung cancer cell lines H1993 and H2073. While H1993 was derived from chemo-naive metastasized tumor, H2073 originated from the chemo-resistant primary tumor from the same patient and exhibits strikingly different drug response profile. To understand the underlying genetic and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Non-Small-Cell Lung
Share to Computational Biology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Drug Resistance, Neoplasm

Share to Epigenesis, Genetic

Share to Gene Dosage

Share to Genomics

Share to Lung Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 24297535
PMCID: PMC3940063

Genes

ABCC4
MET
STK11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrative analysis of two cell lines derived from a non-small-lung cancer patient--a panomics approach.PMID 24297535Read ↗

Single-cell transcriptome analysis demonstrates inter-patient and intra-tumor heterogeneity in primary and metastatic lung adenocarcinomaSemantic proximity Read ↗

Single-cell RNA sequencing and bioinformatics as tools to decipher cancer heterogenicity and mechanisms of drug resistanceSemantic proximity Read ↗

Establishment, characterization, and drug screening of low-passage patient individual non-small cell lung cancer in vitro models including the rare pleomorphic subentitySemantic proximity Read ↗

Pan-cancer whole genome comparison of primary and metastatic solid tumorsSemantic proximity Read ↗

Pan-cancer whole genome comparison of primary and metastatic solid tumorsSemantic proximity Read ↗

Decoding Lung Cancer at Single-Cell LevelSemantic proximity Read ↗

Co-occurring genomic alterations in non-small-cell lung cancer biology and therapySemantic proximity Read ↗

Pan-cancer whole-genome comparison of primary and metastatic solid tumours.Semantic proximity Read ↗

Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events.Semantic proximity Read ↗

Culture and multiomic analysis of lung cancer patient-derived pleural effusions revealed distinct druggable molecular types.Semantic proximity Read ↗

Genome-wide profiling of non-smoking-related lung cancer cells reveals common RB1 rearrangements associated with histopathologic transformation in EGFR-mutant tumors.Semantic proximity Read ↗

A comprehensive transcriptional portrait of human cancer cell lines.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.