Article
Establishment and comparative characterization of novel squamous cell non-small cell lung cancer cell lines and their corresponding tumor tissue.
Lung cancer (Amsterdam, Netherlands) - 1 Jan 2012
Gottschling Sandra, Jauch Anna, Kuner Ruprecht, Herpel Esther, Mueller-Decker Karin, Schnabel Philipp A, Xu Elizabeth C, Muley Thomas, Sültmann Holger, Bender Christian, Granzow Martin, Efferth Thomas, Hoffmann Hans, Dienemann Hendrik, Herth Felix J F, Meister Michael
Abstract excerpt
BACKGROUND: Cell lines play an important role for studying tumor biology and novel therapeutic agents. Particularly in pulmonary squamous cell carcinoma (SCC) the availability of cell lines is limited and knowledge about their representativeness for corresponding tumor tissue is scanty. MATERIALS AND METHODS: We established three novel SCC cell lines from fresh tumor tissue of 28 donors, including 8 SCC. Two cell...
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