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Article

Altered Glycolysis and Mitochondrial Respiration in a Zebrafish Model of Dravet Syndrome.

eNeuro - 1 Jan 2000

Kumar Maneesh G, Rowley Shane, Fulton Ruth, Dinday Matthew T, Baraban Scott C, Patel Manisha

Abstract excerpt

Altered metabolism is an important feature of many epileptic syndromes but has not been reported in Dravet syndrome (DS), a catastrophic childhood epilepsy associated with mutations in a voltage-activated sodium channel, Nav1.1 (SCN1A). To address this, we developed novel methodology to assess real-time changes in bioenergetics in zebrafish larvae between 4 and 6 d postfertilization (dpf). Baseline and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 27066534
DOI: 10.1523/ENEURO.0008-16.2016
PMCID: PMC4820792

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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