Article
Metabolic disruption in Drosophila bang-sensitive seizure mutants.
Genetics - 1 Jul 2006
Fergestad Tim, Bostwick Bret, Ganetzky Barry
Abstract excerpt
We examined a number of Drosophila mutants with increased susceptibility to seizures following mechanical or electrical stimulation to better understand the underlying factors that predispose neurons to aberrant activity. Several mutations in this class have been molecularly identified and suggest metabolic disruption as a possible source for increased seizure susceptibility. We mapped the bang-sensitive seizure...
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