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Article

A whole-animal microplate assay for metabolic rate using zebrafish.

Journal of biomolecular screening - 1 Dec 2008

Makky Khadijah, Duvnjak Petar, Pramanik Kallal, Ramchandran Ramani, Mayer Alan N

Abstract excerpt

Regulation of whole-body metabolism and energy homeostasis has been shown to require signaling between multiple organs. To identify genetic programs that determine metabolic rate, and compounds that can modify it, a whole-animal assay amenable to large-scale screening was developed. The direct correlation of acid production with metabolic rate was exploited to use a noninvasive colorimetric assay for acid...

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PMID: 19029015
DOI: 10.1177/1087057108326080

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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