Article
Effect of intensive atorvastatin therapy on coronary atherosclerosis progression, composition, arterial remodeling, and microvascular function.
The Journal of invasive cardiology - 1 Oct 2012
Eshtehardi Parham, McDaniel Michael C, Dhawan Saurabh S, Binongo José Nilo G, Krishnan Sandeep K, Golub Lucas, Corban Michel T, Raggi Paolo, Quyyumi Arshed A, Samady Habib
Abstract excerpt
BACKGROUND: There is a discrepancy between the marked reduction in adverse events with statins and their modest effect on atheroma regression. We hypothesized that, in a Western population, high-dose atorvastatin will result in alterations in coronary atheroma composition, phenotype, and microvascular function. METHODS: Serial coronary radiofrequency intravascular ultrasound (VH-IVUS), coronary flow reserve...
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