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Article

Evolutionarily derived networks to inform disease pathways.

Genetic epidemiology - 1 Dec 2017

Graham Britney E, Darabos Christian, Huang Minjun, Muglia Louis J, Moore Jason H, Williams Scott M

Abstract excerpt

Methods to identify genes or pathways associated with complex diseases are often inadequate to elucidate most risk because they make implicit and oversimplified assumptions about underlying models of disease etiology. These can lead to incomplete or inadequate conclusions. To address this, we previously developed human phenotype networks (HPN), linking phenotypes based on shared biology. However, such...

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Share to Cardiovascular Diseases
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Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genome-Wide Association Study

Share to Metabolic Networks and Pathways

Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 28944497
DOI: 10.1002/gepi.22078
PMCID: PMC5696086

Genes

HPN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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