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Article

Profiling of Cross-Functional Peptidases Regulated Circulating Peptides in BRCA1 Mutant Breast Cancer.

Journal of proteome research - 6 May 2016

Fan Jia, Tea Muy-Kheng M, Yang Chuan, Ma Li, Meng Qing H, Hu Tony Y, Singer Christian F, Ferrari Mauro

Abstract excerpt

Women with inherited BRCA1 mutations are more likely to develop breast cancer (BC); however, not every carrier will progress to BC. The aim of this study was to identify and characterize circulating peptides that correlate with BC patients carrying BRCA1 mutations. Circulating peptides were enriched using our well-designed nanoporous silica thin films (NanoTraps) and profiled by mass spectrometry to identify...

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Source

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Identifiers

PMID: 27058005
DOI: 10.1021/acs.jproteome.6b00010
PMCID: PMC5124559

Genes

BRCA1
CPN1
KLK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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