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Article

Kallikrein-related peptidases: mechanistic understanding for potential therapeutic targeting in cancer

2 Oct 2024

Abstract excerpt

INTRODUCTION: Human kallikrein-related peptidases (KLKs) represent a subgroup of 15 serine endopeptidases involved in various physiological processes and pathologies, including cancer. AREAS COVERED: This review aims to provide a comprehensive overview of the KLK family, highlighting their genomic structure, expression profiles and substrate specificity. We explore the role of KLKs in tumorigenesis, emphasizing...

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PMID: 39431595
DOI: 10.1080/14728222.2024.2415014

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