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Article

Mass spectrometry (LC-MS/MS) identified proteomic biosignatures of breast cancer in proximal fluid.

Journal of proteome research - 5 Oct 2012

Whelan Stephen A, He Jianbo, Lu Ming, Souda Puneet, Saxton Romaine E, Faull Kym F, Whitelegge Julian P, Chang Helena R

Abstract excerpt

We have begun an early phase of biomarker discovery in three clinically important types of breast cancer using a panel of human cell lines: HER2 positive, hormone receptor positive and HER2 negative, and triple negative (HER2-, ER-, PR-). We identified and characterized the most abundant secreted, sloughed, or leaked proteins released into serum free media from these breast cancer cell lines using a combination...

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Source

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Identifiers

PMID: 22934887
DOI: 10.1021/pr300606e
PMCID: PMC3521600

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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