Article
Epicardium-Derived Cells Formed After Myocardial Injury Display Phagocytic Activity Permitting In Vivo Labeling and Tracking.
Stem cells translational medicine - 1 May 2016
Ding Zhaoping, Temme Sebastian, Quast Christine, Friebe Daniela, Jacoby Christoph, Zanger Klaus, Bidmon Hans-Jürgen, Grapentin Christoph, Schubert Rolf, Flögel Ulrich, Schrader Jürgen
Abstract excerpt
UNLABELLED: Epicardium-derived cells (EPDCs) cover the heart surface and can function as a source of both progenitor cells and trophic factors for cardiac repair. Currently, EPDCs cannot be conveniently labeled in vivo to permit imaging and cell tracking. EPDCs formed after myocardial infarction (MI) preferentially take up a perfluorocarbon-containing nanoemulsion (PFC-NE; 130 ± 32 nm) injected 3 days after...
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