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Isolation and characterization of a Sca-1+/CD31-progenitor cell lineage derived from mouse heart tissue

9 Aug 2014

Abstract excerpt

BACKGROUND: Myocardial infarction remains the leading cause of mortality in developed countries despite recent advances in its prevention and treatment. Regenerative therapies based on resident cardiac progenitor cells (CPCs) are a promising alternative to conventional treatments. However, CPCs resident in the heart are quite rare. It is unclear how these CPCs can be isolated and cultured efficiently and what the...

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PMID: 25106452
DOI: 10.1186/1472-6750-14-75

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