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Article

Directed evolution and synthetic biology applications to microbial systems.

Current opinion in biotechnology - 1 Jun 2016

Bassalo Marcelo C, Liu Rongming, Gill Ryan T

Abstract excerpt

Biotechnology applications require engineering complex multi-genic traits. The lack of knowledge on the genetic basis of complex phenotypes restricts our ability to rationally engineer them. However, complex phenotypes can be engineered at the systems level, utilizing directed evolution strategies that drive whole biological systems toward desired phenotypes without requiring prior knowledge of the genetic basis...

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PMID: 27054950
DOI: 10.1016/j.copbio.2016.03.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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