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Article

Directed Evolution of Microbial Communities.

Annual review of biophysics - 6 May 2021

Sánchez Álvaro, Vila Jean C C, Chang Chang-Yu, Diaz-Colunga Juan, Estrela Sylvie, Rebolleda-Gomez María

Abstract excerpt

Directed evolution is a form of artificial selection that has been used for decades to find biomolecules and organisms with new or enhanced functional traits. Directed evolution can be conceptualized as a guided exploration of the genotype-phenotype map, where genetic variants with desirable phenotypes are first selected and then mutagenized to search the genotype space for an even better mutant. In recent years,...

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PMID: 33646814
DOI: 10.1146/annurev-biophys-101220-072829
PMCID: PMC8105285

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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