Article
Directed evolution of metabolic pathways.
Trends in biotechnology - 1 Jan 2006
Chatterjee Ranjini, Yuan Ling
Abstract excerpt
The modification of cellular metabolism is of biotechnological and commercial significance because naturally occurring metabolic pathways are the source of diverse compounds used in fields ranging from medicine to bioremediation. Directed evolution is the experimental improvement of biocatalysts or cellular properties through iterative genetic diversification and selection procedures. The creation of novel...
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