Article

Systems biology approach for metabolomic engineering in Streptomyces : the Phosphoenolpyruvate-Pyruvate-Oxaloacetate node

2015-01-01

Abstract excerpt

The emergence of antibiotic resistance poses a threat to humankind in combination with the significant drop in discovering new antibiotics since the 1980s. Although Streptomyces are prolific producers of bioactive metabolites, genome analysis shows more biosynthetic clusters than compounds produced under laboratory conditions. Besides identification of a new potential compound, its biosynthesis needs to be underst...

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Literature Corpus work: aeab8249-fc35-54b2-b482-407baea34129
DOI: 10.48730/cf2b-td56

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