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Article

Genetic analyses of chr11p15.5 region identify MUC5AC-MUC5B associated with asthma-related phenotypes.

The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Oct 2023

Li Xingnan, Li Huashi, Christenson Stephanie A, Castro Mario, Denlinger Loren C, Erzurum Serpil C, Fahy John V, Gaston Benjamin M, Israel Elliot, Jarjour Nizar N, Levy Bruce D, Mauger David T, Moore Wendy C, Zein Joe, Kaminski Naftali, Wenzel Sally E, Woodruff Prescott G, Bleecker Eugene R, Meyers Deborah A

Abstract excerpt

OBJECTIVE: Genome-wide association studies (GWASs) have identified single nucleotide polymorphisms (SNPs) in chr11p15.5 region associated with asthma and idiopathic interstitial pneumonias (IIPs). We sought to identify functional genes for asthma by combining SNPs and mRNA expression in bronchial epithelial cells (BEC) in the Severe Asthma Research Program (SARP). METHODS: Correlation analyses of mRNA expression...

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Identifiers

PMID: 36946148
DOI: 10.1080/02770903.2023.2193631
PMCID: PMC10524756

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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