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Article

Pro- and anti-inflammatory cytokine gene polymorphism profiles in Bulgarian multiple sclerosis patients.

Journal of neuroimmunology - 1 Nov 2005

Mihailova Snejina, Ivanova Milena, Mihaylova Anastassia, Quin Ludmila, Mikova Olia, Naumova Elissaveta

Abstract excerpt

Dysregulation in the expression of pro- and anti-inflammatory cytokines is one of the milestones in multiple sclerosis (MS) development and progression. The aim of this study was to investigate the possible influence of TNF-alpha (-308), TGF-beta (codons 10 and 25), IL-10 (-1082, -819, -592), IL-6 (-174) and IFN-gamma (+874) polymorphisms on susceptibility to multiple sclerosis (MS). Genotyping was performed by...

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PMID: 16183136
DOI: 10.1016/j.jneuroim.2005.06.020

Genes

TNF

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