Article
Do Variants in GSTs Modify the Association between Traffic Air Pollution and Asthma in Adolescence?
International journal of molecular sciences - 1 Apr 2016
Bowatte Gayan, Lodge Caroline J, Lowe Adrian J, Erbas Bircan, Dennekamp Martine, Marks Guy B, Perret Jennifer, Hui Jennie, Wjst Matthias, Gurrin Lyle C, Allen Katrina J, Abramson Michael J, Matheson Melanie C, Dharmage Shyamali C
Abstract excerpt
Polymorphisms in genes involved in the oxidative stress response may partially explain the documented heterogeneous associations between traffic-related air pollution (TRAP) exposure and asthma and allergies in children. We investigated whether the GSTT1, GSTM1 and GSTP1 gene polymorphisms modified the associations between TRAP exposure during the first year of life and asthma, wheeze and hay fever in...
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