Article
Cell type dependent morphological adaptation in polyelectrolyte hydrogels governs chondrogenic fate.
Biomedical materials (Bristol, England) - 4 Apr 2016
Raghothaman Deepak, Leong Meng Fatt, Lim Tze Chiun, Wan Andrew C A, Ser Zheng, Lee Eng Hin, Yang Zheng
Abstract excerpt
Repair of critical-size articular cartilage defects typically involves delivery of cells in biodegradable, 3D matrices. Differences in the developmental status of mesenchymal stem cells (MSCs) and terminally differentiated mature chondrocytes might be a critical factor in engineering appropriate 3D matrices for articular cartilage tissue engineering. This study examined the relationship between material-driven...
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