Article
hiPS-MSCs differentiation towards fibroblasts on a 3D ECM mimicking scaffold.
Scientific reports - 16 Feb 2015
Xu Ruodan, Taskin Mehmet Berat, Rubert Marina, Seliktar Dror, Besenbacher Flemming, Chen Menglin
Abstract excerpt
Fibroblasts are ubiquitous cells that constitute the stroma of virtually all tissues and play vital roles in homeostasis. The poor innate healing capacity of fibroblastic tissues is attributed to the scarcity of fibroblasts as collagen-producing cells. In this study, we have developed a functional ECM mimicking scaffold that is capable to supply spatial allocation of stem cells as well as anchorage and storage of...
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