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Article

Hypoxia-inducible factor 1-related diseases and prospective therapeutic tools.

Journal of pharmacological sciences - 1 Mar 2004

Park Jong-Wan, Chun Yang-Sook, Kim Myung-Suk

Abstract excerpt

Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that functions as a master regulator of oxygen homeostasis. HIF-1 regulates the expressions of the proteins that increase oxygen delivery, which enables cells to survive in oxygen-deficient conditions. Based on information as to which types of genes are controlled by HIF-1, it appears that HIF-1 provides pathological tissues with survival in hypoxic...

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Identifiers

PMID: 15037806
DOI: 10.1254/jphs.94.221

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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