Article
Functional analysis of the putative fusion domain of the baculovirus envelope fusion protein F.
Journal of virology - 1 Jul 2004
Westenberg Marcel, Veenman Frank, Roode Els C, Goldbach Rob W, Vlak Just M, Zuidema Douwe
Abstract excerpt
Group II nucleopolyhedroviruses (NPVs), e.g., Spodoptera exigua MNPV, lack a GP64-like protein that is present in group I NPVs but have an unrelated envelope fusion protein named F. In contrast to GP64, the F protein has to be activated by a posttranslational cleavage mechanism to become fusogenic. In several vertebrate viral fusion proteins, the cleavage activation generates a new N terminus which forms the...
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