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Article

Acute stress is detrimental to heart regeneration in zebrafish

1 Mar 2016

Abstract excerpt

Psychological stress is one of the factors associated with human cardiovascular disease. Here, we demonstrate that acute perceived stress impairs the natural capacity of heart regeneration in zebrafish. Beside physical and chemical disturbances, intermittent crowding triggered an increase in cortisol secretion and blocked the replacement of fibrotic tissue with new myocardium. Pharmacological simulation of stress...

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PMID: 27030176
DOI: 10.1098/rsob.160012

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