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Advances in understanding the mechanism of zebrafish heart regeneration

19 Jul 2014

Abstract excerpt

The adult mammalian heart was once believed to be a post-mitotic organ without any capacity for regeneration, but recent findings have challenged this dogma. A modified view assigns the mammalian heart a measurable capacity for regeneration throughout its lifetime, with the implication that endogenous regenerative capacity can be therapeutically stimulated in the injury setting. Although extremely limited in...

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PMID: 25127427
DOI: 10.1016/j.scr.2014.07.003

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