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Article

A20 plays a critical role in the immunoregulatory function of mesenchymal stem cells.

Journal of cellular and molecular medicine - 1 Aug 2016

Dang Rui-Jie, Yang Yan-Mei, Zhang Lei, Cui Dian-Chao, Hong Bangxing, Li Ping, Lin Qiuxia, Wang Yan, Wang Qi-Yu, Xiao Fengjun, Mao Ning, Wang Changyong, Jiang Xiao-Xia, Wen Ning

Abstract excerpt

Mesenchymal stem cells (MSCs) possess an immunoregulatory capacity and are a therapeutic target for many inflammation-related diseases. However, the detailed mechanisms of MSC-mediated immunosuppression remain unclear. In this study, we provide new information to partly explain the molecular mechanisms of immunoregulation by MSCs. Specifically, we found that A20 expression was induced in MSCs by inflammatory...

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Identifiers

PMID: 27028905
DOI: 10.1111/jcmm.12849
PMCID: PMC4956951

Genes

TNF
MSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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